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Opinion|Videos|July 12, 2024

Where Does Axatilimab Fit in the Treatment Lineup?

Author(s)Corey S. Cutler, MD, MPH, FRCPC, Hannah Choe, MD

Experts on graft-vs-host disease discuss the potential role for axatilimab within current treatment algorithms.

Episodes in this series

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 1 Overview of Acute/Chronic GVHD

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 2 Review of MOA and Effectiveness of Current Treatments

Corey Cutler, MD, MPH, an expert on GVHD

EP. 3 Axatilimab, Anti-CSF1R, a New Treatment Class

Hannah Choe, MD, an expert on GVHD

EP. 4 Unmet Needs in the Management of cGVHD

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 5 AGAVE-201 Trial Review

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 6 Where Does Axatilimab Fit in the Treatment Lineup?

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 7 Next Steps in the Development of Axatilimab

Video content above is prompted by the following questions:

What were the key findings from the AGAVE-201 trial presented at the 2023 ASH meeting?
- How did the different dosing regimens of axatilimab compare in terms of objective response rates, duration of response, and steroid dose reduction?
  - Were there any notable differences in efficacy or safety profiles observed across the different treatment arms?

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