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Opinion|Videos|July 9, 2024

Axatilimab, Anti-CSF1R, a New Treatment Class

Author(s)Corey S. Cutler, MD, MPH, FRCPC, Hannah Choe, MD

Corey Cutler, MD, MPH, discusses how axatilimab’s mechanism of action differs from currently available therapies for patients with chronic GVHD.

Episodes in this series

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 1 Overview of Acute/Chronic GVHD

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 2 Review of MOA and Effectiveness of Current Treatments

Corey Cutler, MD, MPH, an expert on GVHD

EP. 3 Axatilimab, Anti-CSF1R, a New Treatment Class

Hannah Choe, MD, an expert on GVHD

EP. 4 Unmet Needs in the Management of cGVHD

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 5 AGAVE-201 Trial Review

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 6 Where Does Axatilimab Fit in the Treatment Lineup?

Corey Cutler, MD, MPH, and Hannah Choe, MD, experts on GVHD

EP. 7 Next Steps in the Development of Axatilimab

Video content above is prompted by the following questions:

As a first in class anti-CSF-1R antibody, please discuss how axatilimab's novel mechanism of action differs from current chronic GVHD (cGVHD) therapies?
- How significant is it to target the CSF-1/ CSF-1R pathway in cGVHD pathogenesis?

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