Danielle Bucco | Authors

Articles

Expert Discusses ZUMA-2 Trial Investigating CAR T-Cell Therapy in MCL

April 25, 2018

While relapsed/refractory mantle cell lymphoma (MCL) is considered an aggressive disease, new findings show patients may benefit from adding chimeric antigen receptor T-cell therapy to their treatment regimen. ZUMA-2, a currently ongoing trial, aims to understand the potential benefits with axicabtagene ciloleucel, an anti-CD19 CAR T-cell product, for patients with relapsed/refractory MCL.

Expert Discusses Novel Treatment Options for Relapsed/Refractory CLL

April 10, 2018

According to Neil E. Kay, MD, novel agents, such as ibrutinib (Imbruvica), venetoclax (Venclexta), idelalisib (Zydelig), and acalabrutinib (Calquence), are revolutionizing treatment for patients with chronic lymphocytic leukemia. However, the best way to sequence these agents to maximize the benefit to patients is still unclear.