Later-Line Combination Therapies Used as Treatment in Multiple Myeloma

Triplets and Quadruplets Now Play Role in Transplant-Ineligible NDMM
October 02, 2024
During a Case-Based Roundtable® event, Andrzej Jakubowiak, MD, PhD, surveyed how newer regimens influence a patient case of a 79-year-old with newly diagnosed multiple myeloma in the second article of a 2-part series.

Tailoring Regimens for Different Age Groups With Multiple Myeloma
August 08, 2024
During a Case-Based Roundtable® event, Andrew Yee, MD, discussed myeloma treatment strategies for different age groups, focusing on personalized regimens and the pros and cons of CAR T-cell therapy and bispecific antibodies in the second article of a 2-part series.

Balancing Treatment Efficacy and Adverse Events in Multiple Myeloma
July 17, 2024
During a Case-Based Roundtable® event, Andrew Yee, MD, discussed the use of carfilzomib-based regimens compared with other options for patients with multiple myeloma, including those refractory to lenalidomide in the first article of a 2-part series.

Assessing The Rationale Behind Triplet Regimens in RRMM
June 14, 2024
During a Case-Based Roundtable® event, Ariel Grajales-Cruz, MD, discussed the long-term results of the phase 3 IKEMA study that build the rationale for use of the triplet therapy isatuximab, carfilzomib, and dexamethasone, in patients with relapsed/refractory multiple myeloma in the second article of a 2-part series.

Isa-Kd Stands Out Among Subsequent Regimens in Multiple Myeloma
April 04, 2024
During a Case-Based Roundtable® event, Cristiana Costa Chase, MD, discussed the recommended regimens and trials supporting therapies following lenalidomide-refractory relapse of multiple myeloma in the second article of a 2-part series.

IKEMA Shows Advantage for Anti-CD38 in 1q21+ R/R Multiple Myeloma
March 22, 2024
During a Case-Based Roundtable® event, Cristiana Costa Chase, MD, discussed the IKEMA trial of isatuximab, carfilzomib, and dexamethasone in patients with relapsed/refractory multiple myeloma in the first article of a 2-part series

Isatuximab-Based Triplet Therapy Improves Outcomes in R/R Multiple Myeloma
January 04, 2024
In the first article of a 2-part series, Douglas Sborov, MD, discusses how the efficacy results of the IKEMA trial not only show isatuximab, carfilzomib, and dexamethasone as a viable treatment option for patients with multiple myeloma, but as further proof triplet therapy is superior to doublet therapy in this patient population.

Isatuximab Provides Longer Survival in Early Relpase Multiple Myeloma
December 11, 2023
In the second article of a 2-part series, Joshua Richter, MD, discusses how the isatuximab, carfilzomib, and dexamethasone regimen fits into the landscape of treatment for patients with early relapsed multiple myeloma.

Isatuximab Combo Provides Durable Option in High-Risk Multiple Myeloma
November 20, 2023
In the first article of a 2-part series, Joshua Richter, MD, discussed how the triplet therapy of isatuximab, carfilzomib and dexamethasone, has impacted treatment considerations for patients with high-risk multiple myeloma.

Reactions to Updated Isatuximab Data in Second-Line Multiple Myeloma
April 05, 2023
During a Targeted Oncology™ Case-Based Roundtable™ event, Suzanne Lentzsch, MD, PhD, discussed with participants their views on the IKEMA trial of isatuximab, carfilzomib, and dexamethasone in patients with multiple myeloma.
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