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Opinion|Videos|December 22, 2025

Emergence and Evolution of ctDNA Assays for MRD in TNBC

Author(s)Marija Balic, MD

Emergence and Evolution of ctDNA Assays for MRD in TNBC

Episodes in this series

EP. 1 TNBC Treatment and the Emergence of MRD Detection Assays

EP. 1 TNBC Treatment and the Emergence of MRD Detection Assays

EP. 2 Emergence and Evolution of ctDNA Assays for MRD in TNBC

EP. 2 Emergence and Evolution of ctDNA Assays for MRD in TNBC

EP. 3 Design and Function of Oncodetect Assay for MRD Detection

EP. 3 Design and Function of Oncodetect Assay for MRD Detection

EP. 4 Remaining Obstacles to Widespread Use of MRD Detection in TNBC

EP. 4 Remaining Obstacles to Widespread Use of MRD Detection in TNBC

Marija Balic, MD, discusses how circulating tumor DNA assays for molecular residual disease detection have evolved in recent years. She details the mechanisms of tumor-informed assays such as Oncodetect, which she used in a subanalysis of the NSABP B-59/GBG-96-GeparDouze trial in triple-negative breast cancer.

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