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Publication|Articles|December 30, 2024

Peers & Perspectives in Oncology

  • December II, 2024
  • Pages: 76

Roundtable Roundup: Relapsed CLL After 2 Prior Lines

Fact checked by: Dylann Bailey

In separate, live virtual events, Alvaro Jose Alencar, MD, and Michael E. Williams, MD, discussed third-line options for a patient with relapsed/refractory chronic lymphocytic leukemia (CLL).
  • CASE SUMMARY
  • A 65-year-old man who was diagnosed with CLL in 2019 presented to his oncologist at routine follow-up.
  • Medical history: type 2 diabetes controlled with insulin
  • Patient received previous treatments with:
    • First line: acalabrutinib (Calquence) monotherapy
    • Achieved good clinical response over 3 years but later progressed on therapy
    • Second line: venetoclax (Venclexta) plus rituximab (Rituxan)
    • Completed 24-month treatment regimen
  • Was in treatment-free interval for 6 months
  • Due to disease progression, his hemoglobin has dropped over the past 3 months and is currently at 10 g/dL.
  • At follow-up, the patient is now aged 70 years and does not report any symptoms yet.
  • ECOG performance status: 0

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about 1 year ago

Cusnir Explores Impact of ARANOTE Data on ARPI Plus ADT Use in mHSPC

about 1 year ago

Telehealth Continues to Show Importance Post COVID-19 in Rare Diseases

about 1 year ago

Managing Intermediate-Risk Myelofibrosis With Ruxolitinib

about 1 year ago

Peers Evaluate CAR T Referral and Bridging Process for Early Relapsed Multiple Myeloma

about 1 year ago

Brunner Discusses Dosing Approaches for ESA and Novel Therapies for Low-Risk MDS

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