Opinion|Videos|January 29, 2024

Selecting a Second-Line Therapy for a Patient With HR+/HER2- mBC After Progression on ET + CDK4/6i Therapy

Author(s)Virginia G. Kaklamani, MD

Virginia Kaklamani, MD, DSc, shares that in deciding second-line therapy for metastatic breast cancer after CDK4/6 inhibitors, endocrine sensitivity guides the choice between treatments based on ESR1/PIK3CA mutations and safety profiles with/without fulvestrant injections.

Episodes in this series

EP. 1 Patient Case: A 56-Year-Old Woman with HR+/HER2- Metastatic Breast Cancer and Visceral Metastases

EP. 1 Patient Case: A 56-Year-Old Woman with HR+/HER2- Metastatic Breast Cancer and Visceral Metastases

EP. 2 Unmet Needs in the Treatment of Patients With Metastatic Breast Cancer With Visceral Metastases

EP. 2 Unmet Needs in the Treatment of Patients With Metastatic Breast Cancer With Visceral Metastases

EP. 3 The Impact of Biomarkers in Clinical Decision-Making and Emergent Agents in HR+/HER2- Metastatic Breast Cancer

EP. 3 The Impact of Biomarkers in Clinical Decision-Making and Emergent Agents in HR+/HER2- Metastatic Breast Cancer

EP. 4 Review of EMERALD Subgroup Analysis Data From SABCS 2023

EP. 4 Review of EMERALD Subgroup Analysis Data From SABCS 2023

EP. 5 Selecting a Second-Line Therapy for a Patient With HR+/HER2- mBC After Progression on ET + CDK4/6i Therapy

EP. 5 Selecting a Second-Line Therapy for a Patient With HR+/HER2- mBC After Progression on ET + CDK4/6i Therapy

EP. 6 Management Approaches for HR+/HER2- mBC Based on Metastasis Location and Disease Burden

EP. 6 Management Approaches for HR+/HER2- mBC Based on Metastasis Location and Disease Burden

EP. 7 Management of Adverse Events in Patients With HR+/HER2- Metastatic Breast Cancer

EP. 7 Management of Adverse Events in Patients With HR+/HER2- Metastatic Breast Cancer

EP. 8 Future Directions in the Treatment of Patients With HR+/HER2- Metastatic Breast Cancer

EP. 8 Future Directions in the Treatment of Patients With HR+/HER2- Metastatic Breast Cancer

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