Selecting Atezolizumab Plus Bevacizumab Versus Ipilimumab Plus Nivolumab in RCC

Brian I. Rini, MD

Brian I. Rini, MD, professor of medicine at the Cleveland Clinic, discusses how data should be looked at between 2 combinations for the treatment of renal cell carcinoma. He says atezolizumab plus bevacizumab will never be compared head to head with ipilimumab plus nivolumab.

Brian I. Rini, MD, professor of medicine at the Cleveland Clinic, discusses how data should be looked at between 2 combinations for the treatment of renal cell carcinoma (RCC). He says atezolizumab (Tecentriq) plus bevacizumab (Avastin) will never be compared head to head with ipilimumab (Yervoy) plus nivolumab (Opdivo).

Having these 2 combinations is great from a clinician standpoint as they are additional options for patients with RCC. One combination could be more tolerable and suitable for some patients than the other combination, Rini says. It is the clinician’s job to then figure out which combination is best.