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Your AI-Trained Oncology Knowledge Connection!

Opinion|Videos|March 14, 2025

Targeting Recurrent and Metastatic NPC With Systemic Immunotherapy: The Role of Toripalimab and Insights From Radiation Oncology

Author(s)Shravan Kandula, MD

An expert discusses the treatment approach for recurrence in Case 1, evaluating the combination of toripalimab + gemcitabine/cisplatin for recurrent disease and considering the potential for re-irradiation, while also reflecting on the treatment strategy in Case 2 and the criteria for determining whether the patient would benefit from additional radiation therapy.

Episodes in this series

EP. 1 Introduction to Clinical Cases: Toripalimab in Recurrent and Metastatic NPC

EP. 1 Introduction to Clinical Cases: Toripalimab in Recurrent and Metastatic NPC

EP. 2 Considerations for NPC Therapy: Clinical Perspectives From Radiation Oncology

EP. 2 Considerations for NPC Therapy: Clinical Perspectives From Radiation Oncology

EP. 3 Targeting Recurrent and Metastatic NPC With Systemic Immunotherapy: The Role of Toripalimab and Insights From Radiation Oncology

EP. 3 Targeting Recurrent and Metastatic NPC With Systemic Immunotherapy: The Role of Toripalimab and Insights From Radiation Oncology

EP. 4 Monitoring Treatment Response in NPC: Looking to EBV Titers and Imaging

EP. 4 Monitoring Treatment Response in NPC: Looking to EBV Titers and Imaging

EP. 5 Evolving Paradigms: The Role of Systemic Immunotherapy in NPC Treatment

EP. 5 Evolving Paradigms: The Role of Systemic Immunotherapy in NPC Treatment

Video content above is prompted by the following:

Please comment on the treatment approach for recurrence in Case 1.
What are your thoughts on toripalimab + gemcitabine/cisplatin for recurrent disease?
Would you consider re-irradiation in this patient?
What are your thoughts on the treatment approach in Case 2?
How do you determine whether the patient would benefit from the addition of radiation therapy?

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