June 2013 | The Journal of Targeted Therapies in Cancer

Novel Proteasome Inhibitors for Multiple Myeloma

June 25, 2013

Clinical Articles

The recent approval of the second-generation proteasome inhibitor carfilzomib by the FDA comes nine years after the initial approval of bortezomib, the first-in-class drug of its type.

Sorafenib Doubles PFS in DTC

June 24, 2013

Clinical Articles

Interim findings from a phase III study indicate that sorafenib nearly doubled PFS for patients with differentiated thyroid cancer resistant to standard radioactive iodine therapy.

The Promise of Circulating Tumor Cells

June 20, 2013

Clinical Articles

Although the use of CTCs as a “liquid biopsy” to detect tumor growth has long been a goal, developing the technology for detecting and analyzing CTCs has been a challenge.

Radium-223 in Advanced Prostate Cancer

June 17, 2013

Clinical Articles

The progression of prostate cancer to castration-resistant prostate cancer is a crucial change in the behavior of this cancer. Bony metastasis is a common finding that may cause symptoms such as pain.