Hannah Slater | Authors


Bemcentinib/Pembrolizumab Shows Clinical Activity, Tolerability in Advanced NSCLC

January 29, 2021

Patients with checkpoint inhibitor-naïve and refractory composite AXL-positive non—small cell lung cancer, responded to treatmen with the first-in-class oral kinase inhibitor bemcentinib in combination with pembrolizumab, and the compound was well-tolerated, according to updated results from the phase 2 BGBC008 clinical trial.

Safety of Pembrolizumab With Capecitabine and Bevacizumab Demonstrated in MSS mCRC

January 15, 2021

Immunotherapy with pembrolizumab in combination with capecitabine-based chemotherapy and the VEGF inhibitor bevacizumab, appeared tolerable as treatment of patients with microsatellite stable metastatic colorectal cancer, showing a safety profile that was expected with the drug, results from a phase 2 study show.

Survival Improved With Tucatinib Regimen in HER2-Positive Metastatic Breast Cancer

September 21, 2020

Statistically significant and clinically meaningful improvements in both progression-free survival and overall survival were observed with the addition of tucatinib to trastuzumab and capecitabine as treatment of patients with HER2-positive metastatic breast cancer, irrespective of the presence of brain metastases.

CAR T-Cell Therapy With Axi-Cel Holds Promise in R/R Indolent NHL

May 30, 2020

Interim analysis of the ZUMA-5 study indicates that patients with relapsed or refractory indolent non-Hodgkin lymphoma who were treated with the chimeric antigen receptor T-cell therapy of axicabtagene ciloleucel had high rates of response and demonstrated the agent's manageable safety profile.

Novel LuPSMA Appears More Active in Metastatic Castration-Resistant Prostate Cancer

May 29, 2020

“Lu-PSMA is a novel class of therapy with high activity and relatively low toxicity, consistent with the results of prior single-center studies in phase II data. Lu-PSMA appears to represent a favorable treatment option compared to cabazitaxel in a selected population with high PSMA-expression.”