John Mascarenhas, MD, reviews the case of a 76-year-old woman with myelofibrosis and her treatment with pacritinib.
EP. 1: Case Presentation: A 76-Year-Old Woman with Myelofibrosis
John Mascarenhas, MD, presents the case of a 76-year-old woman with myelofibrosis and provides his initial impressions.
EP. 2: Clinical Phenotypes in Patients with Myelofibrosis
Dr John Mascarenhas explains the differences between myelofibrosis phenotypes and why it affects treatment regimen choices.
EP. 3: Considerations in Choosing a Treatment for Myelofibrosis
An expert describes the factors he considers when choosing a treatment for a patient with myelofibrosis, and how he judges treatment response.
EP. 4: Mechanism of Action of Pacritinib
Dr John Mascarenhas reviews the mechanism of action of pacritinib, a selective JAK2 inhibitor.
EP. 5: Review of the PERSIST-1 and PERSIST-2 Trials
John Mascarenhas, MD, describes his personal experience with using pacritinib to treat patients with myelofibrosis and reviews the study design and outcomes for both the PERSIST-1 and PERSIST-2 trials.
EP. 6: The Future of Myelofibrosis Treatment
Dr John Mascarenhas looks to the future of myelofibrosis treatment and shares some ongoing clinical trials and potential treatments that excite him.
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