A 76-Year-Old Woman with Myelofibrosis

John Mascarenhas, MD, reviews the case of a 76-year-old woman with myelofibrosis and her treatment with pacritinib.

EP. 1: Case Presentation: A 76-Year-Old Woman with Myelofibrosis

April 20th 2022

John Mascarenhas, MD, presents the case of a 76-year-old woman with myelofibrosis and provides his initial impressions.

EP. 2: Clinical Phenotypes in Patients with Myelofibrosis

April 20th 2022

Dr John Mascarenhas explains the differences between myelofibrosis phenotypes and why it affects treatment regimen choices.

EP. 3: Considerations in Choosing a Treatment for Myelofibrosis

April 20th 2022

An expert describes the factors he considers when choosing a treatment for a patient with myelofibrosis, and how he judges treatment response.

EP. 4: Mechanism of Action of Pacritinib

April 20th 2022

Dr John Mascarenhas reviews the mechanism of action of pacritinib, a selective JAK2 inhibitor.

EP. 5: Review of the PERSIST-1 and PERSIST-2 Trials

April 20th 2022

John Mascarenhas, MD, describes his personal experience with using pacritinib to treat patients with myelofibrosis and reviews the study design and outcomes for both the PERSIST-1 and PERSIST-2 trials.

EP. 6: The Future of Myelofibrosis Treatment

April 20th 2022

Dr John Mascarenhas looks to the future of myelofibrosis treatment and shares some ongoing clinical trials and potential treatments that excite him.