First-Line Therapy With Bispecific Antibody for EGFR-Mutated NSCLC

Amivantamab/Lazertinib Maintains OS Benefit in EGFR+ NSCLC
January 15, 2025
During a Case-Based Roundtable® event, Joshua K. Sabari, MD, continued discussion of key outcomes from the MARIPOSA trial and toxicity management in patients with EGFR-mutated non–small cell lung cancer in the second article of a 2-part series.

MARIPOSA Trial Shows PFS Benefit With or Without CNS Disease in NSCLC
December 24, 2024
During a Case-Based Roundtable® event, Joshua K. Sabari, MD, discussed the mechanism of action of amivantamab and the MARIPOSA trial in patients with EGFR-mutated non–small cell lung cancer in the first article of a 2-part series.

Emphasizing the Need for NGS in Advanced NSCLC to Determine Treatment
April 23, 2024
During a Case-Based Roundtable® event, Joshua Sabari, MD, led a discussion on the need for next-generation sequencing to determine treatment in patients with EGFR-positive advanced non–small cell lung cancer in the first article of a 2-part series.

Selection of First-Line NSCLC Therapy Influenced by Delayed Testing
March 08, 2024
During a Targeted Oncology™ Case-Based Roundtable™ event, Misako Nagasaka, MD, PhD, asked participants how they would approach therapy for a patient with metastatic non–small cell lung cancer when biomarker testing is not yet completed. This is the second of 2 articles based on this event.

Comprehensive Molecular Testing Needed for Frontline NSCLC Treatment
February 19, 2024
During a Targeted Oncology™ Case-Based Roundtable™ event, Misako Nagasaka, MD, PhD, held a discussion on the use of biomarker testing in patients with advanced non–small cell lung cancer. This is the first of 2 articles based on this event.

Areas of Concern in Using Amivantamab and Mobocertinib in EGFR Exon 20+ NSCLC
May 11, 2023
During a Targeted Oncology™ Case-Based Roundtable™ event, Joshua K. Sabari, MD, discussed with participants how they would use the FDA-approved therapies amivantamab and mobocertinib for patients with non–small cell lung cancer and an EGFR exon 20 insertion alteration.
This is the second of 2 articles based on this event.

Amivantamab Compared With Real-World EGFR Exon 20 NSCLC Population
April 26, 2023
During a Targeted Oncology™ Case-Based Roundtable™ event, Joshua K. Sabari, MD, discussed research supporting the use of amivantamab for patients with non–small cell lung cancer and an EGFR exon 20 insertion, including data comparing with real-world cohorts of similar patients treated with other agents.

Results of Amivantamab and Mobocertinib Trials Evaluated for Use in NSCLC
August 03, 2022
During a Targeted Oncology case-based roundtable event, Christine Bestvina, MD, discussed the outcomes of clinical trials of the EGFR exon 20-targeted agents amivantamab and mobocertinib with participants.
This is the second of 2 articles based on this event.
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