Advancements in Frontline EGFR-Mutated NSCLC

An expert discusses emerging frontline treatments for EGFR-mutated non–small cell lung cancer (NSCLC), highlighting the evolving role of regimens like FLORA2 and MARIPOSA, and emphasizing the shift toward personalized, patient-centered therapy strategies.

An expert discusses the MARIPOSA study’s impact on managing central nervous system (CNS) involvement in EGFR-mutated non–small cell lung cancer, emphasizing improved brain progression-free survival, dual-targeted resistance prevention, and a promising shift toward more effective and personalized treatment strategies.

An expert discusses efforts to improve the tolerability and delivery of the MARIPOSA regimen, highlighting subcutaneous amivantamab from the Paloma studies and proactive skin care strategies from the Cocoon study as key advances in enhancing patient experience, adherence, and clinical outcomes.

An expert discusses findings from the Paloma-3 study, emphasizing how subcutaneous amivantamab improves patient-reported outcomes and quality of life, reinforcing a growing oncology focus on treatment experience, tolerability, and patient-centered care alongside clinical efficacy.

An expert discusses the successful long-term use of amivantamab in frontline regimens like MARIPOSA, emphasizing the importance of proactive adverse effect management, patient education, and team-based care in supporting adherence and delivering sustainable, patient-centered cancer treatment.

An expert discusses the evolving treatment landscape for EGFR-mutated non–small cell lung cancer (NSCLC), highlighting the frontline shift of targeted therapies like those in MARIPOSA, the growing complexity of treatment sequencing, and the importance of patient education and clinical trial participation in navigating this transformative era of care.