The Expanding Continuum of Care in Metastatic Breast Cancer | Evolving Paradigms

Current Breast Cancer Landscape and Targeted Therapies for HER2 Overexpression

September 16, 2020

Clinical Articles

Breast cancer is the most common cancer that affects women, with estimates that it will account for 30% of all new cancer diagnoses in women in 2020. As the most commonly overexpressed receptor in breast cancer, HER2 is amplified or overexpressed in about 15% of breast cancers, leading to dysregulated cell proliferation. This article explores the current breast cancer landscape, with a focus on emerging HER2-targeted therapies, and discusses the unmet needs within the treatment landscape.