July 2016

Receptor Tyrosine Kinase Inhibitors Show Only Modest Potential in Sarcoma

July 21, 2016

Clinical Articles

Research is making only modest progress in the discovery of receptor tyrosine kinase inhibitors that show benefit in the treatment of sarcomas, Gary K. Schwartz, MD, argued during a presentation at the 2016 ASCO Annual Meeting.

TKIs Competing for Frontline Therapy in ALK+ NSCLC

July 25, 2016

Clinical Articles

Deciding the sequencing order of therapies for patients with ALK-positive non–small cell lung cancer (NSCLC) is a challenge, as new information on next-generation tyrosine kinase inhibitors (TKIs) comes to light, says Robert Doebele, MD, PhD. Testing for ALK translocations can help to determine which therapies NSCLC patients should be receiving, but questions regarding the sequencing of ALK inhibitors still remain.

Liver-Directed Therapies Crucial in Metastatic Colorectal Cancer

July 25, 2016

Clinical Articles

Liver metastases have long led to a poor diagnosis for patients with metastatic colorectal cancer (mCRC), especially when the metastases are unresectable. However, an increasing number of adjunct techniques can treat the liver until surgery becomes possible, and there are also alternatives to surgery for nonresectable patients.