Updated guidance recommends biennial prostate-specific antigen testing for average-risk men aged 50 to 69 years and annual screening beginning at age 45 for higher-risk men.
Commentary|Articles|March 16, 2015
Agents Targeted Against PSMA for Prostate Cancer
Author(s)Scott Tagawa, MD, MS, FACP, FASCO
Scott T. Tagawa, MD, MS, associate professor, Clinical Medicine and Urology, Weill Cornell Medical College, discusses PSMA-targeting agents for the treatment of prostate cancer.
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Clinical Pearls
Scott T. Tagawa, MD, MS, associate professor, Clinical Medicine and Urology, Weill Cornell Medical College, discusses PSMA-targeting agents for the treatment of prostate cancer.
- As resistance to AR-targeted therapy develops, PSMA expression will increase in many patients. An agent targeted against PSMA could be added in at this time.
- PSMA-targeted therapy could also potentially be used in combination with AR-targeted therapy.
- Both AR- and PSMA-targeted therapies are being investigated in clinical trials and are already making an impact.
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