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Commentary|Articles|March 17, 2015

Agents Targeted Against PSMA for Prostate Cancer

Scott T. Tagawa, MD, MS, associate professor, Clinical Medicine and Urology, Weill Cornell Medical College, discusses PSMA-targeting agents for the treatment of prostate cancer.

Clinical Pearls

Scott T. Tagawa, MD, MS, associate professor, Clinical Medicine and Urology, Weill Cornell Medical College, discusses PSMA-targeting agents for the treatment of prostate cancer.

  • As resistance to AR-targeted therapy develops, PSMA expression will increase in many patients. An agent targeted against PSMA could be added in at this time.
  • PSMA-targeted therapy could also potentially be used in combination with AR-targeted therapy.
  • Both AR- and PSMA-targeted therapies are being investigated in clinical trials and are already making an impact.

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