Dong Chen, MD, PhD, discusses how AI has changed the landscape for genomic testing and patient management.
AI has truly revolutionized healthcare, profoundly enhancing both patient management and the efficiency of medical testing. Its impact is evident across several critical domains, ushering in an era of more precise and proactive medical interventions. In an interview with Targeted OncologyTM, Dong Chen, MD, PhD, hematopathologist and vice chair of practice in pathology in the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, MN, discusses how AI has changed this landscape.
In the laboratory setting, AI algorithms are becoming indispensable tools. Clinicians have recently integrated them into our practices, not necessarily for developing new tests, but primarily to augment the ability to thoroughly investigate complex cases. This includes sifting through vast amounts of data to pinpoint rare events, particularly in specialized areas like molecular diagnostics and flow cytometry. The exploration and implementation of AI in these processes are ongoing, with some facilities already experiencing significant improvements in their analytical capabilities. This helps lab professionals work more efficiently and accurately, ensuring that even the most subtle indicators of disease are not overlooked.
The realm of medical imaging has seen a dramatic transformation thanks to AI, approaching it from 2 distinct yet complementary angles. Firstly, AI is facilitating the incorporation of novel biomarkers into imaging studies, exemplified by AI-assisted prostate imaging that offers greater diagnostic clarity. Secondly, AI is crucial for the seamless integration of multi-omic data into the interpretation of images. These advancements are instrumental in boosting both the sensitivity and specificity of imaging studies, making it considerably easier to detect elusive or rare findings. In situations where clinicians are essentially searching for "a needle in a haystack"—like identifying minute abnormalities in complex scans—AI significantly improves accuracy, leading to earlier and more precise diagnoses.
On the clinical front, the potential of AI and machine learning is being rigorously explored for their predictive power. The ultimate goal is to enable proactive and automated ordering of tests to verify suspicions of a patient's potential high risk of relapse. Researchers are leveraging vast amounts of clinical data to train AI models. For instance, by analyzing routine information such as complete blood counts (CBCs), the recovery rates of cell counts, patient symptoms, and other biomarkers, AI aims to accurately predict the likelihood of a patient experiencing a relapse. This predictive capability promises to transform how clinicians monitor and intervene in patient care, leading to more timely and effective treatments and ultimately, a more complete healthcare solution.