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Commentary|Videos|December 17, 2025

Pumitamig Plus Chemo Yields Promising Results in Early Data

Fact checked by: Paige Britt

Pumitamig shows promise as a bispecific antibody, enhancing immunotherapy effectiveness in treating triple-negative breast cancer patients.

In an interview at the 2025 San Antonio Breast Cancer Symposium, Peter Schmid, MD, PhD, Barts Cancer Institute in London, England, discussed the preliminary data from a global multicohort phase 2 randomized trial of pumitamig plus chemotherapy for patients with locally advanced/metastatic triple negative breast cancer.

Schmid detailed the rationale of combining pumitamig and chemotherapy and how the combination can aid patients in the first or second-line setting. Schmid noted that confirmed responses are approximately 62%, and the unconfirmed responses are approximately 72%.

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