An Analysis of the PROCLAIM 2007-2012 National Registry

Gregory A. Daniels, MD, PhD, Associate Clinical Professor of Medicine, Division of Hematology-Oncology, University of California, San Diego, discusses the findings of the 2007-2012 PROCLAIM national registry.

Clinical Pearls:

• IL-2 is an immunotherapy that can give complete responses that last years
• The database retrospectively looked back over a 5-year period
• The registry showed that IL-2 still gives an occasional, durable response
• The registry also showed that clinical factors such as normal LDH and patient performance status is important in determining who will be successful on IL-2
• Patients with stable disease or did not seem to respond to IL-2 initially had better overall survival than previously thought, according to the registry findings

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