Considerations When Treating Patients With Stage II Colon Cancer

Cristian Tomasetti, PhD, discusses the clinical questions that exist among physician who treat patient with stage II colon cancer.

Cristian Tomasetti, PhD, assistant professor at the John Hopkins School of Medicine Health, discusses the clinical questions that exist among physicians who treat patient with stage II colon cancer.

Following surgery, deciding which patient should get treatment is the most immediate consideration. Physicians must also think about the duration of treatment, which includes when to stop treatment or switch patients to a more effective treatment.

Questions also exist about understanding relapse and being able to identify patients who will relapse in order to select better therapies, explains Tomasetti. Further, there is an unmet need for technologies that can help identify patients who are responding to treatment, and those who are not.


0:07 | There are many, many questions about how to treat a patient after surgery. And so, in the setting of adjuvant chemotherapy, as you can imagine, question ranges from who should get it? Do you know do all patients need adjuvant chemotherapy afterwards or not? That's an important question. And if a patient gets it, when the treatment should stop, for example, or do we have ways to understand who of the patients that just had surgery is going to relapse? And so, can we can distinguish the group of patients that you know, need this treatment versus those that don't really, and several more questions, of course.

1:59 | For example, once a patient is under treatment, not just want to stop but can we determine if or how the patient is responding to treatment? In there may be the potential with new technologies to determine whether the patient is responding well to a given treatment or not. And so, you know, when should if and when should we switch a patient to a different treatment, for example, if there is developmental resistance? So, there are many many questions related to what to do after a patient had surgery for stage two colon cancer

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