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Opinion|Videos|June 5, 2025

First-Line Treatment Approaches for EGFR-mutated Metastatic NSCLC: Updates from MARIPOSA High-Risk Analyses

An expert discusses a treatment approach for the patient case above, how factors like brain metastases influence first-line treatment choices, reviews high-risk/CNS outcomes data from MARIPOSA and FLAURA2, and shares their impression of icPFS and DoR from MARIPOSA, along with how to determine which patients are best suited for either combination treatment option.

Episodes in this series
  • Please discuss a treatment approach for the patient case above.
  • How do factors like brain metastases influence your 1L treatment choice?
  • How do you determine which patients are best suited for either combination treatment option?

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