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Commentary|Videos|March 15, 2026

How ctDNA Testing is Changing Lymphoma Treatment

Fact checked by: Paige Britt

MRD testing promises sharper DLBCL response tracking than PET scans, cutting false positives, biopsies, and guiding therapy as trials catch up.

In an interview with Targeted Oncology, Hua-Jay “Jeff” Cherng, MD, assistant professor of medicine in the lymphoma program in the Division of Hematology and Oncology at the Columbia University Irving Medical Center, discussed how circulating tumor DNA testing is changing the way doctors monitor response to treatment compared with traditional PET scans.

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