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Bladder Cancer
Stay up to date on practice-changing data in community practice.
Evaluating Neoadjuvant and Adjuvant Therapies and Benefits for MIBC
During a live event, Matthew Galsky, MD, discussed adjuvant and neoadjuvant treatment approaches for muscle-invasive bladder cancer.
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BCG Plus Mitomycin Shows Similar Efficacy, Fewer Doses in NMIBC
The ANZUP 1301 trial showed that BCG and mitomycin showed similar DFS to BCG alone in NMIBC, but with 40% fewer BCG doses and similar safety.
FDA Clears IND for Novel Nectin-4 Targeted Radiopharmaceutical Across Cancers
A phase 1b trial plans to evaluate AKY-1189 for the treatment of Nectin-4–expressing tumors.
FDA ODAC Votes 5 to 4 Against UGN-102 for Recurrent LG-IR-NMIBC
The FDA ODAC decided that the overall benefit-risk of the investigational therapy UGN-102 is not favorable in patients with recurrent low-grade, intermediate-risk NMIBC.
First-Line Disitamab Vedotin/Toripalimab Shows Benefit in HER2+ la/mUC
Disitamab vedotin plus toripalimab showed significant survival benefits vs chemo in first-line HER2+ advanced urothelial carcinoma, with a manageable safety profile.
Durvalumab Plus BCG Improves Survival in Early Bladder Cancer
Durvalumab plus full BCG significantly improved disease-free survival in high-risk early bladder cancer vs BCG alone in the POTOMAC trial.