
Commentary|Articles|September 22, 2026
What to Watch at IMS 2026: Defining Cure as Multitargeting, CELMoDs, and In Vivo CAR T Move Forward
Author(s)Jonah Feldman
Fact checked by: Sabrina Serani
Preview the 2026 International Myeloma Society meeting: the IMS/IMWG cure consensus, plenary session phase 3 trials, and new bispecific/CAR T myeloma findings.
Advertisement
Advertisement
The 23rd International Myeloma Society (IMS) Annual Meeting & Exposition, taking place September 23-26, 2026, in Glasgow, Scotland, will showcase a number of key trials in the newly diagnosed and relapsed settings, including new bispecific antibodies, cereblon E3 ligase modulators (CELMoDs), and multitargeting combinations. Notably, it will devote much of its scientific program to a question that has taken hold in the myeloma community over the past year: how close has multiple myeloma (MM) come to being a curable disease?
Related to this article

During a live event, Rushang Patel, MD, PhD, and participants discussed referral timing, bridging, and payer barriers that shape access to cellular therapy in early relapsed multiple myeloma.

Aman Chauhan, MD, reviews DAREON-7 data on obrixtamig plus chemotherapy in DLL3-positive neuroendocrine carcinoma, including response rates by DLL3 level.

Jacob Sands, MD, of Dana-Farber Cancer Institute, discusses survival gains, durability, and safety of tarlatamab plus durvalumab in the phase 3 DeLLphi-305 trial.

Imneskibart showed promising outcomes and tolerability in patients who had previously received immune checkpoint inhibition for either melanoma or lung adenocarcinoma.

Renuka Iyer, MD, explains how NCCN is digitizing its guidelines with structured data to support AI tools, prior authorization, and point-of-care access.

Arvind Dasari, MD, MS, reviews key advances in neuroendocrine tumors, including new PRRT options, alpha emitters, cabozantinib, and clinical trials.

Arvind N. Dasari, MD, MS, reviews a year in neuroendocrine tumors marked by expanding radioligand options, improved classification, and disappointing combination therapies.
Advertisement
Advertisement
