Dr. Jessica Frakes on Monitoring Recurrences in HPV-Positive Oropharyngeal Squamous Cell Carcinoma
Frakes says the number of HPV-positive oropharyngeal cancer diagnoses year to year is growing, though the number of survivors is proportionate.
Jessica Frakes, MD, assistant professor of radiation oncology, Department of Radiation Oncology, Moffitt Cancer Center, discusses patients treated with definitive radiation therapy (RT) for HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) and the detection of recurrences. Frakes says the number of HPV-positive oropharyngeal cancer diagnoses year to year is growing, though the number of survivors is proportionate.
According to Frakes, most recurrences and toxicities were found by posttreatment imaging at 3 months and physical examinations during the 6 months after treatment. She said patients experienced a low rate of permanent toxicity. Previous retrospective and prospective studies have shown that while HPV-associated cases of OPSCC are increasing in frequency, treatments result in decreased toxicities and increased survival.
APG-157 Earns FDA Fast Track Designation for Head and Neck Cancer Treatment
August 23rd 2024With this designation, the sponsor of APG-157 is eligible for more frequent interaction with the FDA, facilitating faster drug development and review for this neoadjuvant head and neck cancer therapy.
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