What are the principle treatment goals for this patient with advanced, invasive myxoid liposarcoma?
Overall, the goals of treatment in a patient with mixoid liposarcoma is curative. When a patient has a primary mixoid liposarcoma, we evaluate the aggressiveness of the tumor by looking at the grade as well as the round cell component. Patients with a high-grade aggressive tumor, close margins, higher round cell component will be treated with chemotherapy, radiation therapy, and surgery. A smaller size tumor with very low round cell component may be treated with surgery alone plus or minus radiation therapy.
CASE: Soft-Tissue Sarcoma Case 2
Michael C is a 59-year-old social worker from Los Angeles California; his medical history is notable for obesity, COPD, and mild hypertension.
In September of 2014, Michael returns for follow up and his CT scan shows a 4 cm posterior mediastinal mass, and a 6 cm perinephric mass suspicious for metastatic disease. He initiates treatment with anthracycline and ifosfamide chemotherapy (6 cycles) for recurrent disease and shows a partial response.
Need for Systemic Therapy Remains in Sarcoma
November 27th 2023In an interview with Targeted Oncology, Lisa B. Ercolano, MD, discussed the evolving treatment landscape for sarcomas and underscored the pivotal role of molecular profiling, while addressing the need for more efficacious systemic therapies.
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Sarcoma Awareness Month: Impact of Molecular Testing and Individualized Treatments
July 19th 2023For Sarcoma Awareness Month, Lisa B. Ercolano, MD, and Mark Agulnik, MD, discussed the importance of understanding the genomics of sarcomas and how molecular testing can be useful in this space.
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