Dr. Jose P. Zevallos on Tobacco-Related Mutations in HPV-Positive Oropharyngeal SCC

Zevallos says the study consisted of 66 patients and found that there were distinct genomic differences between HPV-positive smokers and non-smokers.

Jose P. Zevallos, MD, MPH, FACS, assistant professor, director of Oncologic Research, University of North Carolina School of Medicine, discusses a recent study that looked at molecular profiles determined by targeted DNA sequencing of patients with HPV-positive oropharyngeal squamous cell carcinoma (SCC). The purpose of the study was to determine if patients with HPV-positive oropharyngeal SCC, who were also smokers, had a different mutational status than non-smokers.