|Videos|July 9, 2018

Treatment Options and Care for Patients Who Develop Therapy-Related AML

Case: A 67-Year-Old Man with Therapy-Related AML

A 67-year-old man who had received CHOP for diffuse large B-cell lymphoma 3 years prior
PMH: hypertension controlled with amlodipine
Laboratory results:
- WBC 15 x 10⁹/L
- Serum creatinine 1.5 mg/dL
- Normal LFTs
- LVEF 50%
Diagnosis: Acute Myeloid Leukemia
ECOG PS 1
The patient received liposomal cytarabine and daunorubicin
His course was complicated by febrile neutropenia
After induction, <5% marrow blasts, neutrophil count (>1400/µL), platelets 60,000/µL

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