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Opinion|Videos|July 24, 2024

Management of Adverse Events – IO/IO and IO/TKI

Author(s)Matthew T. Campbell, MD, MS, Rana R. McKay, MD

The panelists compare the adverse event profiles of immunotherapy combination (IO/IO) versus immunotherapy plus tyrosine kinase inhibitor (IO/TKI) regimens, and address the economic implications of managing long-term side effects.

Episodes in this series

2 KOLs are featured in this program.

EP. 1 Current treatment options for ccRCC based on patient and disease factors

2 KOLs are featured in this program.

EP. 2 CheckMate-214: Long-term follow-up data

2 KOLs are featured in this program.

EP. 3 Review of CheckMate-214: Long-term follow-up in favorable risk subgroup

2 KOLs are featured in this program.

EP. 4 Review of CLEAR and CheckMate-9ER: Four-Year and 55 Month Follow-Up Data

2 KOLs are featured in this program.

EP. 5 Review of KEYNOTE-426: Five-year Follow-up Data

2 KOLs are featured in this program.

EP. 6 Discontinuation or Continuation of IO Therapy – IO/IO vs. IO/TKI Regimens

2 KOLs are featured in this program.

EP. 7 Treatment-free survival in IO/TKI

2 KOLs are featured in this program.

EP. 8 Biomarkers: Impact on Treatment Choices and Future Expectations

2 KOLs are featured in this program.

EP. 9 Management of Adverse Events – IO/IO and IO/TKI

2 KOLs are featured in this program.

EP. 10 New formulations for current therapies – SC vs. IV

2 KOLs are featured in this program.

EP. 11 Novel Agents/Combinations for aRCC

Please discuss adverse events associated with IO/IO vs. IO/TKI regimens.
- What impact do the AE profiles of these combinations have on your selection of systemic therapy for treatment-naïve patients with aRCC?
- What is the financial impact of managing long-term AEs?

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