Case: 75-Year-Old Man Diagnosed With Polycythemia Vera January 2018 A 75-year old man presents to PCP for routine evaluation; feels well but complains of pruritus exacerbated by hot showers PE: Unremarkable PMH: No prior history of thrombosis, hypertension managed with statin Lab values: HGB: 18.9 g/dL Hct: .56 L/L RBC: 68 x 1012/L WBC: 10.6 x 109/L Serum EPO: 4.1 mU/mL Bone Marrow biopsy declined Cytogenetics: JAK-V617Fmutation