IMiD Sequencing in Relapsed Multiple Myeloma with Paul G. Richardson, MD Case 1
IMiD Sequencing in Relapsed Multiple Myeloma with Paul G. Richardson, MD
Case Scenario 1:
July 2011
- The patient is a 61-year-old Caucasian female who was diagnosed with stage II MM. Genetic testing showed her to have t(4:16). At the time she was treated with lenalidomide, bortezomib, and dexamethasone (RVD) induction therapy followed by autologous stem cell transplantation.
- She achieved a partial response with RVD and remained in remission. Based on her high-risk cytogenetics, the patient was placed on lenalidomide maintenance therapy.
August 2016
- Routine follow up shows that her M-protein levels have now risen to 1.4 g/dL and her light chain levels continue to rise.
- Although she has developed mild anemia and her creatinine level is slightly elevated to 1.3 mg/dL, she continues to work full-time, has no bone pain, and a has a normal calcium level.
Related Videos
Related Content
Isa-Kd Stands Out Among Subsequent Regimens in Multiple Myeloma
April 4th 2024Article
During a Case-Based Roundtable® event, Cristiana Costa Chase, MD, discussed the recommended regimens and trials supporting therapies following lenalidomide-refractory relapse of multiple myeloma in the second article of a 2-part series.
Read More
Benefit of Dara-Rd Maintained Across Age Groups in Transplant-Ineligible NDMM
April 2nd 2024Article
During a Case-Based Roundtable® event, Laahn Foster, MD, discussed the SWOG S0777 and MAIA trials in transplant-ineligible newly diagnosed multiple myeloma in the second article of a 2-part series.
Read More
