Hear how a single ctDNA blood draw 3 to 9 weeks into immunotherapy may reveal response earlier than imaging in NSCLC, with Valsamo Anagnostou, MD, PhD.
Feature|Articles|February 18, 2026
Precision Oncology and the New Era of Lung Cancer
Author(s)Sabrina Serani, Bruna Pellini, MD
Fact checked by: Andrea Eleazar, MHS
Discover how precision lung cancer care tackles gene fusions, new HER2/ROS1/ALK drugs, expanded screening, and liquid biopsies shaping 2026 treatment.
Advertisement
Advertisement
The landscape of thoracic oncology has undergone a seismic shift over the last 2 decades. Where once a diagnosis of advanced lung cancer offered few paths forward, the advent of precision medicine has transformed the field into one of the most dynamic areas of modern medicine. Bruna Pellini, MD, chief of Thoracic Medical Oncology at Baptist Health Miami Cancer Institute, specializes in treating uncommon mutations and discussed how to navigate the increasingly complex web of targeted therapies.
Related to this article
Arvind Dasari, MD, MS, reviews key advances in neuroendocrine tumors, including new PRRT options, alpha emitters, cabozantinib, and clinical trials.
Aman Chauhan, MD, discusses combining intratumoral Seneca Valley virus (SVV-001) with ipilimumab and nivolumab in neuroendocrine cancer.
Nikolaos Trikalinos, MD, reviews CABINET data showing cabozantinib improved PFS in functional and nonfunctional NETs without added grade 3 toxicity.
Mark A. Lewis, MD, explains how oral cabozantinib reduces time toxicity for patients with previously treated, well-differentiated neuroendocrine tumors.
Amr Mohamed, MD, reviews zocilurtatug pelitecan phase 1/2 data in platinum-refractory extrapulmonary neuroendocrine carcinoma.
Halfdan Sorbye, MD, PhD, discusses why accurately distinguishing NET G3 from NEC is critical, as the wrong first-line therapy can shorten survival.
Chrisann Kyi, MD, discusses the 79.3% response rate with sofetabart mipitecan plus bevacizumab in platinum-sensitive ovarian cancer and phase 3 plans.
Advertisement
Advertisement