Outcomes in Newly Diagnosed Transplant-Ineligible Multiple Myeloma

Video

Outcomes in Newly Diagnosed Transplant-Ineligible Multiple Myeloma

Case: 83-Year-Old Man With NDMM Ineligible for Transplant

History and Presentation:

  • 83-year-old man c/o back pain and fatigue
  • Cardiac stent placed 3 years ago; high blood pressure; BMI 32

Diagnostic Workup:

  • Laboratory findings
    • M-protein 3.8 g/dL
    • Hb 7.9 g/dL
    • LDH 290 IU/L
    • Albumin 3.9 g/dL
    • β2-microglobulin 4.25 mg/L
    • Creatinine 1.5 mg/dL
    • FLC kappa 134 mg/dL

  • Bone marrow biopsy
    • Good cellularity with 60% bone marrow plasma cells
  • Cytogenetics/FISH: standard-risk, no cytogenetic abnormalities
  • Imaging
    • MRI of the spine: multiple focal lesions; moderate diffuse infiltration of spine, pelvis, and proximal femurs.
  • ECOG PS: 2
  • Durie-Salmon PLUS Stage IIIA IgG multiple myeloma requiring treatment with symptomatic anemia and bone lesions

Treatment:

Patient was started on D-Rd

Recent Videos
Jamie L. Koprivnikar, MD, an expert on MDS
Jamie L. Koprivnikar, MD, an expert on MDS
Jamie L. Koprivnikar, MD, an expert on MDS
Jamie L. Koprivnikar, MD, an expert on MDS
Jamie L. Koprivnikar, MD, an expert on MDS
Related Content