
Recent advances in treating Philadelphia chromosome-positive acute lymphoblastic leukemia offer hope for long-term remission without transplant, highlighting TKI discontinuation's potential.

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Elisabetta Abruzzese, MD, PhD, is in the Department of Hematology at S. Eugenio University, both in Rome, Italy.

Recent advances in treating Philadelphia chromosome-positive acute lymphoblastic leukemia offer hope for long-term remission without transplant, highlighting TKI discontinuation's potential.

Recent studies reveal promising outcomes for discontinuing TKI therapy in select patients with Philadelphia chromosome-positive acute lymphoblastic leukemia, suggesting potential long-term remission.

Careful management by a team of specialists is needed to balance disease control and fetal health in patients with CML who are pregnant or trying to become prengant.

Published: September 19th 2024 | Updated:

Published: June 27th 2025 | Updated: