Howard M. Sandler, MD, MS, FASTRO

Howard M. Sandler, MD, MS, FASTRO, Chair, Radiation Oncology, Ronald H. Bloom Family Chair, Cancer Therapeutics, Cedars Sinai, discusses patient benefit and toxicities of a phase III study of docetaxel with hormonal and radiation therapy of patients with prostate cancer.

Sandler said that he and his colleagues enrolled men with very high-risk prostate cancer. Half of the patients had gleason 9 or 10, and most of the rest had gleason 8, with a very high PSA. This was a subset of patients with aggressive disease, so they represent the group that is most likely to benefit, adds Sandler.

Toxicities with the addition of docetaxel were expected. An increase in mild to moderate hematological toxicity was observed.

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Howard M. Sandler, MD, MS, FASTRO, Cedars Sinai, discusses patient benefit and toxicities of a phase III study of docetaxel with hormonal and radiation therapy of patients with prostate cancer.

Dr. Sandler Discusses Docetaxel With Hormonal and Radiation Therapy in Patients With Prostate Cancer

Sandler states that prostate cancer is one of the four most common cancers, with the other three being breast, lung, and colon. The data from this study is the first to show an indication that agiment chemotherapy may have a role in localized non-metastatic prostate cancer.

Going forward, Sandler would like to allow the data to mature more than four years so that they can have more data to work with.

Howard M. Sandler, MD, MS, FASTRO, Chair, Radiation Oncology, Ronald H. Bloom Family Chair, Cancer Therapeutics, Cedars Sinai, discusses the significance of a phase III study on docetaxel with hormonal and radiation therapy in prostate cancer.

Howard M. Sandler, MD, MS, FASTRO | Authors

Articles

Dr. Sandler Discusses Docetaxel With Hormonal and Radiation Therapy in Patients With Prostate Cancer

Significance of a Phase III Study on Docetaxel With Hormonal & Radiation Therapy in Prostate Cancer

Howard M. Sandler, MD, MS, FASTRO | Authors

Articles

Dr. Sandler Discusses Docetaxel With Hormonal and Radiation Therapy in Patients With Prostate Cancer

Significance of a Phase III Study on Docetaxel With Hormonal &amp; Radiation Therapy in Prostate Cancer

Significance of a Phase III Study on Docetaxel With Hormonal & Radiation Therapy in Prostate Cancer