Kim M. Hirshfield MD, PhD | Authors


Oncogenic TSHR Mutation in Papillary Thyroid Cancer

March 04, 2016

We present a case of a 49-year-old woman with a pT4aN1B papillary thyroid cancer who underwent radical thyroidectomy with bilateral neck dissection and RAI I-131 ablation, but poorly tolerated TSH suppression therapy due to tachycardia. Rising thyroglobulin levels and lymph node mapping showed recurrent/progressive disease in the thyroid bed.