Ralph V. Boccia, MD

Case Impressions: 66-Year-Old Man With mCSPC

Case: A 66-Year-Old Male with Metastatic Castrate-Sensitive Prostate Cancer

A 66-year-old man presented with mild intermitted back pain

PMH: DM; medically controlled; OTC analgesics for pain

PE: DRE revealed an enlarged prostate; otherwise unremarkable



Core needle biopsy with TRUS showed adenocarcinoma of prostate

Bone scan revealed 4 spinal lesions (T8/T9, L1/L2) and 1 in the right femur

Chest/abdominal/pelvic CT scan was negative for distant metastases

He was started on ADT + apalutimide 240 mg qDay

Recommendations for using AR-targeted therapy as an approach when managing patients with metastatic castrate-sensitive prostate cancer.