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World GI Congress | Conferences
Tiragolumab-Atezolizumab Combo Shows Preliminary Clinical Activity in Metastatic Esophageal Cancer
July 03, 2021
The combination regimen was well tolerated with promising preliminary anti-tumor activity in patients with heavily pretreated esophageal cancer, who had not received immunotherapy.
Deep, Durable Responses Continue With Pembrolizumab and Trastuzumab in Gastric/GEJ Cancer
July 03, 2021
“We observed much more deeper responses and more meaningful responses [in the treatment arm] compared with the placebo arm, in which 15% of the population had deep responses of ≥ 80%."
Testing for Rare Genomic Alterations in Colorectal Cancer
July 02, 2021
Michael J. Overman, MD, discusses the advances in testing for rare genomic alterations in colorectal cancer.
BRAF Mutant Allele Fraction May Be Prognostic Biomarker for Targeted Therapy Regimens for BRAF V600E+ mCRC
July 02, 2021
A biomarker analysis utilized liquid biopsies to find potential prognostic and predictive biomarkers for patients with BRAF V600E–mutant metastatic colorectal cancer treated with BRAF, EGFR, and/or MEK inhibitors.
Paclitaxel and GSK2636771 Combo Shows Benefit in Certain Patients with Gastric Cancer
July 02, 2021
The combination of paclitaxel and GSK2636771 showed encouraging antitumor activity and a manageable toxicity profile and in patients with PTEN-deficient advanced gastric cancer who progressed after first line chemotherapy.
Overall Survival Improved With 177 Lu-Dotatate for Patients With Progressive Midgut NETs
July 02, 2021
Final overall survival and long-term safety results of the phase 3 NETTER-1 trial were presented during the World Congress on Gastrointestinal Cancer 2021.
Pooled Data Suggest Obese Patients With CRC May Benefit From Weight-Based Chemotherapy Doses
July 02, 2021
Findings from the OCTOPUS Consortium of trial data have indicated that obese patients with colorectal cancer have a poorer survival from adjuvant chemotherapy treatment due to reduced treatment dose and average cumulative relative dose.
New Early-Onset Colon Cancer Data Reinforce Need to Reduce Unnecessary Antibiotic Use
July 02, 2021
In a first-of-its-kind study, data reveal that unnecessary antibiotic use may increase the risk of colon cancer—especially in people under age 50. Findings were presented at the 2021 World Congress on Gastrointestinal Cancer.
Avapritinib Shows Promise in Chinese Patient Population With PDGFRA D842V-Mutant GIST
July 01, 2021
Treatment with avapritinib in Chinese patients with PDGFRA D842V-mutant gastrointestinal stromal tumors revealed promising clinical benefit, according to a bridging study of the NAVIGATOR trial.
AP128 Vaccine Shows Preliminary Safety in Stage IV CRC
July 01, 2021
Scott Kopetz, MD, PhD, FACP, reviews the results of the phase 1b multicenter KISIMA-01 study, for which he presented preliminary results during the ESMO World Congress of Gastrointestinal Cancer 2021.