Metastatic Cutaneous Squamous Cell Carcinoma
Metastatic Cutaneous Squamous Cell Carcinoma
Case: A 79-Year-Old Male With Metastatic CSCC
April 2016
- A 79-year-old male presented to dermatologist with a large ulcerative lesion on clavicle; he reported lesion first appeared 5 months ago while living in Florida for the winter
- Diagnosed with localized cutaneous squamous cell carcinoma
- Standard surgical excision performed with 4 mm clinical margins; postoperative margins negative
May 2018
- Patient returns to dermatologist for follow-up c/o multiple lesions on shoulder and neck around the site of prior excision
- PE:
- Multiple visible, ulcerated lesions, approximately 2-3cm in diameter; suspected tumor depth >5mm
- Multiple palpable nodes ~2cm
- Imaging confirmed 7 mm invasion into subcutaneous fat; parotid nodal involvement
- Biopsy confirmed cutaneous squamous cell carcinoma, poorly-differentiated
- Diagnosis: Metastatic cutaneous squamous cell carcinoma
- Stage IV: T3N2M0
- Patient started on cemiplimab
mRNA-4157 Plus Pembrolizumab Continues to Improve RFS in High-Risk Melanoma
December 18th 2023Findings from 3-year follow-up of KEYNOTE-942/mRNA-4157-P201 show that the cancer vaccine mRNA-4157 plus pembrolizumab reduced the risk of recurrence or death in patients with stage III/IV melanoma following resection.
Read More
Managing Expectations of Treatment for Infiltrative Basal Cell Carcinoma
November 10th 2023In an event comoderated by Michael K. Wong, MD, PhD, FRCPC, and Anokhi Jambusaria, MD, MSCE, the 2 key opinions leaders discussed the hypothetical patient case of an 88-year-old man with a nonhealing ulcer on the lateral aspect of his nose who received a diagnosis of infiltrative basal cell carcinoma.
Read More
