Dr. Daniel Petrylak on Early Trials for Urothelial Bladder Cancer Treatment
Daniel P. Petrylak, MD, talks about taking the clinical trials examining MPDL3280A a step further for bladder cancer patients.
Daniel P. Petrylak, MD, professor of Medicine (Medical Oncology) and of Urology, professor and co-director, Signal Transduction Research Program, Yale Cancer Center, talks about taking the clinical trials examining MPDL3280A (antiPD-L1) a step further.
Petrylak says patients with a high level of PD-L1 expression who are treated with the drug often have better responses than those without. Moreover, while MPDL3280A is still in its infancy, the treatment could be evolved into something that may be able to help a wider range of patients in the future, he adds.
NIAGARA Trial Results Show Durvalumab/Chemo Improves EFS, OS in Cisplatin-Eligible MIBC
September 15th 2024In the NIAGARA trial, significant event-free survival and overall survival gains were observed with neoadjuvant durvalumab plus chemotherapy, followed by adjuvant durvalumab in cisplatin-eligible bladder cancer.
Read More
Extended Follow-Up Bolsters Adjuvant Pembrolizumab DFS Rate in MIUC
September 15th 2024Longer follow-up from the phase 3 AMBASSADOR trial showed adjuvant pembrolizumab to demonstrate a statistically significant and clinically meaningful improvement in disease-free survival in patients with high-risk muscle-invasive urothelial carcinoma.
Read More
