Dr. Hamilton Discusses Challenges With Approved Treatments for HER2-Positive Breast Cancer

Video

Erika P. Hamilton, MD, associate director, Breast Cancer and Gynecologic Cancer Research Program, principal investigator, Sarah Cannon Research Institute, discusses the challenges associated with utilizing new agents in HER2-positive breast cancer.

Many novel agents were recently approved, including T-DM1 (Kadcyla) and pertuzumab (Perjeta). This has made it difficult to determine how to best sequence and use these types of treatments, says Hamilton. There have been approvals for metastatic, neoadjuvant, and adjuvant disease, as well as improvements to the standard treatment trastuzumab (Herceptin).

Hamilton believes the challenges for the next couple of years include figuring out where to sequence the drugs, where to place them, and how best to use them in combination.

Erika P. Hamilton, MD, associate director, Breast Cancer and Gynecologic Cancer Research Program, principal investigator, Sarah Cannon Research Institute, discusses the challenges associated with utilizing new agents in HER2-positive breast cancer.

Related Videos
Video 5 - "Second-Line Treatment Considerations and Improving Outcomes in Breast Cancer"
Video 4 - "Impressions on Safety Data from EMERALD Subgroup Analysis"
Video 2 - "Importance of Biomarker Testing in Breast Cancer"
Video 3 - "EMERALD: Elacestrant for ER+/HER2- Advanced Breast Cancer"
Video 1 - "Patient Profile: A 49-Year-Old Woman with HR+/HER2- mBC and Liver and Lung Metastases"
Video 7 - "Unmet Needs and Future Directions in HER2+ Breast Cancer"
Related Content