Opinion|Videos|November 25, 2024

Episode 2: Incidence of ESR1 mutations and best practices for testing

Author(s)Rahul Gosain, MD, Rohit Gosain, MD, Paolo Tarantino, MD

Along with the Oncology Brothers, Paolo Tarantino, MD, discusses how ESR1 mutations are commonly observed in hormone receptor-positive breast cancer after prolonged endocrine therapy, and emphasizes the importance of molecular testing for ESR1 mutations at both the initial diagnosis of MBC and at each subsequent progression using liquid biopsy assays.

Episodes in this series

EP. 1 Overview of phase 3 EMERALD study of elacestrant for ER+, HER2- MBC

EP. 1 Overview of phase 3 EMERALD study of elacestrant for ER+, HER2- MBC

EP. 2 Episode 2: Incidence of ESR1 mutations and best practices for testing

EP. 2 Episode 2: Incidence of ESR1 mutations and best practices for testing

EP. 3 Co-occurrence of ESR1 mutations with other alterations

EP. 3 Co-occurrence of ESR1 mutations with other alterations

EP. 4 Elacestrant as second-line therapy for ESR1-mutated, endocrine-sensitive disease

EP. 4 Elacestrant as second-line therapy for ESR1-mutated, endocrine-sensitive disease

EP. 5 EMERALD subgroup analysis: Elacestrant in endocrine-sensitive disease

EP. 5 EMERALD subgroup analysis: Elacestrant in endocrine-sensitive disease

EP. 6 Elacestrant: Clinical Pearls for Adverse Effect Management

EP. 6 Elacestrant: Clinical Pearls for Adverse Effect Management

EP. 7 Emerging data on oral selective estrogen receptor degraders

EP. 7 Emerging data on oral selective estrogen receptor degraders

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