Case: A 74-Year-Old Male With Recurrent Metastatic CSCC
November 2017
A 74-year-old male from Florida, with history of multiple resections of CSCC on neck, back and shoulders presents with new deep lesion that exhibited perineural invasion and c/o palpable left axillary mass
Imaging confirmed 6cm left axillary nodal conglomerate
Patient treated with neoadjuvant cisplatin/5FU for 3 cycles
Surgical resection of primary lesion; Lymphadenectomy revealed CSCC involvement in 12 out of 16 resected lymph nodes
May 2018
Follow-up scans revealed early disease progression with multiple pulmonary nodules
Patient started on carboplatin/paclitaxel for 3 cycles
November 2018
Repeat imaging showed disease progression in pulmonary nodules and multiple lymphadenopathies; mediastinal, left and right axillary; bone metastases
Patient started on cemiplimab for 3 cycles
February 2019
Reimaging PET-CT revealed reduction in size and metabolic activity of right and left axillary, and mediastinal lymphadenopathies; pulmonary nodules had considerable reduction in size and were no longer substantial