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|Videos|July 9, 2014
The Tolerability of Sorafenib in Thyroid Cancer
Author(s)Marcia S. Brose, MD, PhD, FASCO
Marcia S. Brose, MD, PhD, assistant professor, Abramson Cancer Center, Department of Otolaryngology, Head & Neck Surgery, Department of Medicine, Division of Hematology/Oncology, Department of Dermatology, University of Pennsylvania, discusses the tolerability and safety of sorafenib as seen in patients with thyroid cancer.
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Marcia S. Brose, MD, PhD, assistant professor, Abramson Cancer Center, Department of Otolaryngology, Head & Neck Surgery, Department of Medicine, Division of Hematology/Oncology, Department of Dermatology, University of Pennsylvania, discusses the tolerability and safety of sorafenib as seen in patients with thyroid cancer.
Clinical Pearls:
- Sorafenib is well tolerated.
- Only one treatment-related death was seen in the DECISION trial, which looked at sorafenib for patients with locally advanced or metastatic radioactive iodine-refractory differentiated thyroid cancer (RAI-rDTC).
- Most of the side effects from the drug, including hand-foot skin reaction, other skin rashes, alopecia and nausea, are controllable with over the counter medications.
- Some patients are even able to maintain their work schedule while being treated with sorafenib.
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