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Opinion|Videos|January 2, 2025

Updates From COMMANDS at ASH 2024

Author(s)Thomas W. LeBlanc, MD, MA

Thomas W. LeBlanc, MD, MA, discusses how the COMMANDS study, which compared luspatercept to epoetin alfa in erythropoiesis-stimulating agent (ESA)–naive, transfusion-dependent patients with low-risk myelodysplastic syndromes (LR-MDS), demonstrated the long-term clinical value of luspatercept in improving hemoglobin levels and reducing transfusion dependence, with updated efficacy results presented by Garcia-Manero et al at ASH 2024.

Episodes in this series

EP. 1 An Overview of the Treatment Landscape for Anemia Management in LR-MDS

EP. 1 An Overview of the Treatment Landscape for Anemia Management in LR-MDS

EP. 2 Updates From COMMANDS at ASH 2024

EP. 2 Updates From COMMANDS at ASH 2024

EP. 3 The Role of Luspatercept in the Evolving Treatment Landscape of LR-MDS

EP. 3 The Role of Luspatercept in the Evolving Treatment Landscape of LR-MDS

EP. 4 Considerations for Treatment Sequencing in LR-MDS

EP. 4 Considerations for Treatment Sequencing in LR-MDS

EP. 5 Academic Perspectives on Health-Related Quality of Life From COMMANDS at ASH 2024

EP. 5 Academic Perspectives on Health-Related Quality of Life From COMMANDS at ASH 2024

EP. 6 Best Practices and Strategies for Luspatercept in the Treatment of LR-MDS

EP. 6 Best Practices and Strategies for Luspatercept in the Treatment of LR-MDS

Video content above is prompted by the following:

Discuss the long-term clinical value from the COMMANDS study of luspatercept vs epoetin alfa in patients with ESA-naive, transfusion-dependent LR-MDS.
First, briefly introduce COMMANDS: study design and key efficacy results
Then, discuss the long-term responses

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