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Anita Shaffer

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Articles


Durable Complete Remissions Achieved in NHL Following CAR T

Durable Complete Remissions Achieved in NHL Following CAR T

December 8th 2019

Complete remissions were achieved in greater than 20% of patients with highly refractory non-Hodgkin lymphomas who had been previously been treated with chimeric antigen receptor T-cell therapy with Mosunetuzumab, a novel bispecific antibody, according to study results presented at the 2019 American Society of Hematology Annual Meeting.


New Approaches Target Overcoming Resistance to TKIs in EGFR+ NSCLC

New Approaches Target Overcoming Resistance to TKIs in EGFR+ NSCLC

June 2nd 2019

The treatment of&nbsp;<em>EGFR</em>-mutant non&ndash;small cell lung cancer has experienced significant improvements with the&nbsp;development of tyrosine kinase inhibitors, but resistance mechanisms that promote disease recurrence have tampered the runaway success of these revolutionary agents, said&nbsp;Katerina A. Politi, PhD, during the 2019 ASCO Annual Meeting. Early findings are presented for 2 novel agents aiming to potentially overcome resistance.&nbsp;


Novel Immune Checkpoint Identified as Promising Target for Blockade Strategies

Novel Immune Checkpoint Identified as Promising Target for Blockade Strategies

November 12th 2016

A new immune checkpoint called PVRIG has emerged as a ripe target for anticancer therapy in solid tumors and an antibody that blocks its ability to suppress an antitumor response is in development.<br /> &nbsp;

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