Maria-Victoria Mateos, MD, PhD

Maria-Victoria Mateos, MD, PhD, director of the Myeloma Unit at University Hospital of Salamanca-IBSAL Salamanca, Spain, discusses the key takeaways from the findings from the phase III ALCYONE trial for patients with multiple myeloma.

At a median follow-up of 28 months, data confirmed that the addition of daratumumab (Darzalex) to bortezomib, melphalan, and prednisone (VMP) is significantly superior to VMP alone, says Mateos. This is confirmed in terms of overall response rate, complete response rate, and progression-free survival (PFS).

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&#8203;Maria-Victoria Mateos, MD, PhD, discusses the key takeaways from the findings from the phase III ALCYONE trial for patients with multiple myeloma.

Key Takeaway Points in Phase III ALCYONE Trial for Multiple Myeloma

Maria-Victoria Mateos, MD, PhD, a physician and director of the myeloma program at the University of Salamanca, Spain, discusses the key takeaways from the phase III ALCYONE trial looking at bortezomib (Velcade), melphalan, and prednisone (VMP) in combination with daratumumab (Darzalex; DARA; D-VMP) in patients with newly diagnosed multiple myeloma who are transplant ineligible.

After a median follow-up of 28 months, D-VMP was superior to VMP in terms of overall response rate, complete response rate, and progression-free survival (PFS), Mateos says. PFS acted as a surrogate marker for overall survival.

Maria-Victoria Mateos, MD, PhD, discusses the key takeaways from the phase III ALCYONE trial looking at bortezomib, melphalan, and prednisone in combination with daratumumab in patients with newly diagnosed multiple myeloma who are transplant ineligible.

Maria-Victoria Mateos, MD, PhD | Authors

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