April 2019

A Multidisciplinary Approach Meets the Needs of Patients With Liver Cancer

April 02, 2019

Clinical Articles

Because of the complex nature of diagnosing, treating, and managing hepatocellular carcinoma, a multidisciplinary approach in the community setting can provide optimal care to patients with the disease.

Challenges Persist With CAR T-Cell Therapy in Pancreatic Cancer

April 02, 2019

Clinical Articles

The success of chimeric antigen receptor T-cell therapy observed in hematologic malignancies has not yet translated into the solid tumor setting; however, efforts continue to try to bring this new modality into the treatment paradigm for solid tumors, including pancreatic cancer.

Surgeons' Association Calls for Change in National Breast Cancer Guidelines

April 02, 2019

Clinical Articles

It is rare that treatment guidelines make sweeping changes to treatment recommendations, yet the American Society of Breast Surgeons is urging that the National Comprehensive Cancer Network guidelines on breast cancer treatment be changed to indicate that genetic testing be offered to all patients with breast cancer.

Safety, Efficacy Results Bolster the Use of LuPSMA in Advanced Prostate Cancer

April 03, 2019

Clinical Articles

The novel targeted radiation therapy, lutetium 177 prostate-specific membrane antigen, demonstrated safety and therapeutic efficacy in 22 patients with metastatic castration-resistant prostate cancer, based on findings presented during the ESMO 2019 International Congress on Targeted Anticancer Therapies.

Rizvi Discusses the Clinical Relevance of Plasma and Tumor TMB

April 03, 2019

Clinical Articles

Naiyer A. Rizvi, MD, explained, in a presentation at the European Society of Medical Oncology 2019 International Congress on Targeted Anticancer Therapies, that plasma assays for determining TMB are becoming more diagnostically relevant.

Investigators Work to Identify Genomic Correlates of Response to Immunotherapy

April 03, 2019

Clinical Articles

At the 2019 American Society of Clinical Oncology–Society for Immunotherapy of Cancer Clinical Immuno-Oncology Symposium, Natalie Vokes, MD, MPhil, reviews the latest evidence linking tumor mutational burden to outcome in patients treated with immune checkpoint blockade as well as genomic correlates of response within the tumor immunity cycle.

Immune Checkpoint Inhibitors Approach Frontline Setting in Head and Neck Squamous Cell Cancer

April 05, 2019

Clinical Articles

Immune checkpoint inhibitors as monotherapy and in combinations regimens are producing promising efficacy data in metastatic head and neck cancers, depite struggles in finding the right treatment settings and patient population subsets.