Predicting Outcomes in Breast Cancer

Charles M. Perou, PhD, professor of genetics, pathology & laboratory medicine, UNC Lineberger Comprehensive Cancer Center, discusses the future of predicting outcomes in breast cancer.

Clinical Pearls

Charles M. Perou, PhD, professor of genetics, pathology & laboratory medicine, UNC Lineberger Comprehensive Cancer Center, discusses the future of predicting outcomes in breast cancer.

  • The utility of genomic tests for prognosis is well established and growing in use in breast cancer. Prediction is the next stage.
  • Results from the CALGB 40601 study demonstrate that tumor subtype and microenvironment is potentially predictive of pCR rate.
  • The best way to measure microenvironment remains to be seen.